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Frontiers | Adrenergic Mechanisms of Audiogenic Seizure ...
https://www.frontiersin.org/articles/10.3389/fnins.2021.581048/full#:~:text=In%20adult%20D%2F%2B%20mice%2C%20audiogenic%20seizures%20are%20non-fatal,behavioral%2C%20electrographical%2C%20and%20cardiorespiratory%20characteristics%20as%20spontaneous%20seizures.
Audiogenic Seizures in the Fmr1 Knock-Out Mouse Are ...
https://pubmed.ncbi.nlm.nih.gov/31666356/
Audiogenic seizures (AGSs) are arguably the most robust behavioral phenotype in the FXS mouse model-the Fmr1 knockout-and may be considered a model of sensory hypersensitivity in FXS. We provide the clearest and most precise genetic evidence to date for the cell types and brain regions involved in causing AGSs in the Fmr1 knockout and, more broadly, for any mouse mutant.
Audiogenic seizure as a model of sudden death in …
https://pubmed.ncbi.nlm.nih.gov/31981213/
Objective: Mouse models of sudden unexpected death in epileptic patients (SUDEP) using audiogenic seizures (AGS) are valuable because death can occur following a sound-induced seizure in the absence of any pharmacologic or electric component. However, only a few strains of mice are AGS prone, and the vast majority of studies involve DBA/2 or DBA/1 inbred strains.
[Audiogenic seizure in the mouse according to strain and ...
https://www.ncbi.nlm.nih.gov/pubmed/6130580
Mice of the DBA/2/M strain are audio-sensitive only for a short period (5 to 10days). When this period is over, 100 p. 100 audiogenic seizures can be obtainedwith experimental magnesium deficiency. When AKR/R, OF1 and C57BL/R mice weredeprived of magnesium for 15 or 21 days, they manifested an audiogenic attackonly when given amphetamine sulfate, caffeine or …
What is the Frings audiogenic seizure sensitive mouse ...
https://brainstuff.org/blog/frings-audiogenic-seizure-sensitive-mouse-epilepsy
The Frings mouse was first described in a 1951 publication in the Journal of Mammalogy (Behavior Patterns of the Laboratory Mouse under Auditory Stress). Genetically, some abnormal element in chromosome 13 called the monogenic audiogenic seizure susceptible (MASS1) gene, produces the phenotype observed in these Frings mice. The mouse was named …
Audiogenic Seizure - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/audiogenic-seizure
Adrenergic Mechanisms of Audiogenic Seizure-Induced …
https://pubmed.ncbi.nlm.nih.gov/33762902/
In adult D/+ mice, audiogenic seizures are non-fatal and have nearly identical behavioral, electrographical, and cardiorespiratory characteristics as spontaneous seizures. In contrast, at postnatal days 20-21, D/+ mice exhibit the same seizure behavior, but have a significantly higher incidence of seizure-induced death following an audiogenic seizure.
Inheritance of Audiogenic Seizure Susceptibility in the …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224327/
Full Text. The Full Text of this article is available as a PDF (643K).. Selected References. These references are in PubMed. This may not be the complete list of references from this article.
Audiogenic Seizures in the Fmr1 Knock-Out Mouse Are ...
https://www.jneurosci.org/content/39/49/9852
Audiogenic seizures (AGSs) are arguably the most robust behavioral phenotype in the FXS mouse model—the Fmr1 knockout—and may be considered a model of sensory hypersensitivity in FXS. We provide the clearest and most precise genetic evidence to date for the cell types and brain regions involved in causing AGSs in the Fmr1 knockout and, more broadly, …
Audiogenic seizure susceptibility is reduced in fragile X ...
https://pubmed.ncbi.nlm.nih.gov/17007840/
The Fmr1 knockout (KO) mouse is characterized by an increased audiogenic seizure (AGS) susceptibility and is considered a good animal model for epilepsy and seizures in the human fragile-X (FRAX) syndrome. Here, we tested the hypothesis that the reintroduction of the FMR1 gene is able to revert the AGS susceptibility characterizing Fmr1 KO mice.
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