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Claudio Soto, PhD | McGovern Medical School
https://med.uth.edu/neurology/faculty/claudio-soto-phd/
Dr. Claudio Soto is the Huffington’s Distinguished University Chair, Professor of Neurology and Director of George and Cynthia Mitchell Center for Alzheimer’s Disease and Related Brain Disorders at The University of Texas Medical School …
Protein misfolding disorders and rational design of ...
https://researchexperts.utmb.edu/en/publications/protein-misfolding-disorders-and-rational-design-of-antimisfoldin
AU - Soto, Claudio. PY - 2006. Y1 - 2006. N2 - Compelling evidence strongly suggests that the conversion of a normal soluble protein into a beta-sheet-rich oligomeric structure and further fibril formation is the critical step in the pathogenesis of several human diseases, termed protein misfolding disorders.
UTIMCO 2006 AR - UTMB
https://www.utimco.org/funds/allfunds/2006annual/st_utmba_06.asp
Thanks to the George and Cynthia Mitchell Research Program in Alzheimer’s Disease, UTMB was able to recruit Dr. Claudio Soto, an internationally recognized authority on protein misfolding disorders. Soto joined UTMB in 2003 to lead the University’s fledgling research program in Alzheimer’s disease.
Blood test for silent phase of prion disease reported - …
https://www.cidrap.umn.edu/news-perspective/2006/07/blood-test-silent-phase-prion-disease-reported
Claudio Soto of the University of Texas Medical Branch (UTMB) in Galveston and colleagues from UTMB and Madrid, Spain, used a "protein misfolding cyclic amplification" (PMCA) assay to detect abnormal prion protein in asymptomatic, scrapie-infected hamsters.
Strongest proof yet found for prion hypothesis ( UTMB ...
http://www.bio-medicine.org/biology-news/Strongest-proof-yet-found-for-prion-hypothesis-458-1/
"For many years, people have tried to make these infectious prions in test tubes, because what is needed to prove the prion hypothesis completely is to be able to produce this process in vitro in the absence of living cells and thus rule out the presence of a virus," said Claudio Soto, professor of neurology at UTMB and senior author of the paper.
Blood test for prion diseases reported | CIDRAP
https://www.cidrap.umn.edu/news-perspective/2005/08/blood-test-prion-diseases-reported
The new blood test was developed by Claudio Soto and two colleagues at the University of Texas Medical Branch at Galveston (UTMB). Writing in Nature Medicne, they report that they devised a way to stimulate a tiny, undetectable amount of abnormal prion protein in a blood sample to multiply so that it reaches detectable levels.
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