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OSX 10.8 Mountain Lion System Sound routing in Audio MIDI ...
https://support.presonus.com/hc/en-us/articles/210046273-OSX-10-8-Mountain-Lion-System-Sound-routing-in-Audio-MIDI-Setup
NOTE: If your issues persist, you can also do the following to reset your Audio options inside of Audio MIDI Setup. 1. Go to this folder. Mac HD/Library/Preferences/Audio . 2. Delete these two files located inside of this folder. 3. Restart your computer and attempt to route the audio through Audio MIDI Setup again. The problem should be resolved.
Duet FireWire with Mountain Lion Dictation - Knowledgebase
https://knowledgebase.apogeedigital.com/hc/en-us/articles/360046455293-Duet-FireWire-with-Mountain-Lion-Dictation
Can't change Output Channels on Audio MIDI Setup - PreSonus
https://support.presonus.com/hc/en-us/articles/210047003-OSX-macOS-Can-t-change-Output-Channels-on-Audio-MIDI-Setup
Open Audio MIDI Setup and configure your Output routing as described above. The Stereo tab should be set to the channels you want to use for playback, per the manual instructions above. The Multichannel tab should be set …
Applications have no audio after Mountain… - Apple Community
https://discussions.apple.com/docs/DOC-4043
If after setting your System Prefences for Audio, your audio doesn't come out after upgrading to Mountain Lion, and resetting the PRAM doesn't help, The Applications -> Utilities -> Audio Midi Setup may need to be unmuted on the various channels of output. Below you'll see an image of the Mountain Lion version of Audio Midi Setup.
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